Skip to main content
Welcome to the new updated!
What is XLH

What is XLH

Symptoms of XLH in adults

Connect the symptoms

XLH affects every adult differently

The symptoms of X-linked hypophosphatemia (XLH) vary from person to person. They can appear at any age and can worsen or change over time. Symptoms affect children and adults differently.

Adults with XLH may experience symptoms in childhood and new symptoms later in life

These include complications such as increased risk of pseudofractures, osteoarthritis, the hardening of ligaments or tendons, as well as a variety of other musculoskeletal symptoms, including pain and stiffness that can decrease mobility and impact daily function.

Symptoms of XLH in adults

Symptoms in adults may include:

Icon of cast to show osteomalacia
(weakening of mature bone)
Icon of adult with short stature being measured by yardstick
Short stature
Icon of two bones forming a joint with pain
Bone and joint pain
Icon of cast to show osteomalacia
Bowed legs and knock knees
Icon of adult with faded legs
Irregularities in walking/balance
(gait abnormalities)
Icon of arm muscle with pain and weakness
Muscle pain and weakness
Icon of teeth with an abscess
Dental abscesses
Icon of a row of teeth with one missing
Tooth loss
Icon of misshapen head
Irregularities in the shape of the head
Icon of headache
often due to structural defects in the back of the skull (Chiari malformations)
Icon of a knee with hardened ligaments
Hardening of ligaments or tendons
Icon of figure with narrowing of spaces in the spinal column
Narrowing of spaces in the spinal column
(spinal stenosis)
Icon of joint with osteoarthritis
Icon of bone with a fracture
Fractures and pseudofractures
(areas of bone weakened by a lack of certain minerals)
Icon of hearing loss
Hearing loss
Icon of battery with low power

My favorite activities for making my stiffness more manageable are taking my dog on walks and doing yoga stretches.”

Living with XLH

View patient stories
Join the community

Sign up to receive helpful resources, get important event invites, and hear real patient stories that will support you on your journey.

Sign up